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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 1
2011 1
2012 5
2013 5
2014 4
2015 11
2016 1
2017 4
2018 3
2019 1
2020 1
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2023 2
2024 0

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38 results

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Page 1
The cuproptosis-related signature associated with the tumor environment and prognosis of patients with glioma.
Wang W, Lu Z, Wang M, Liu Z, Wu B, Yang C, Huan H, Gong P. Wang W, et al. Front Immunol. 2022 Aug 30;13:998236. doi: 10.3389/fimmu.2022.998236. eCollection 2022. Front Immunol. 2022. PMID: 36110851 Free PMC article.
In groups with high-CuproptosisScore, PIK3CA, MUC16, NF1, TTN, TP53, PTEN, and EGFR showed high mutation frequency. IDH1, TP53, ATRX, CIC, and FUBP1 demonstrated high mutation frequency in low-CuproptosisScore group. ...
In groups with high-CuproptosisScore, PIK3CA, MUC16, NF1, TTN, TP53, PTEN, and EGFR showed high mutation frequency. IDH1, TP53, ATRX, CIC, a …
CIC and FUBP1 mutations in oligodendrogliomas, oligoastrocytomas and astrocytomas.
Sahm F, Koelsche C, Meyer J, Pusch S, Lindenberg K, Mueller W, Herold-Mende C, von Deimling A, Hartmann C. Sahm F, et al. Acta Neuropathol. 2012 Jun;123(6):853-60. doi: 10.1007/s00401-012-0993-5. Epub 2012 May 17. Acta Neuropathol. 2012. PMID: 22588899
CIC and FUBP1 mutations have recently been detected in oligodendrogliomas but not in oligoastrocytomas. ...FUBP1 mutations appear to cluster in the DNA binding domain spanning exons 5-14. ...
CIC and FUBP1 mutations have recently been detected in oligodendrogliomas but not in oligoastrocytomas. ...FUBP1 mutations app …
Molecular genetics of gliomas.
Appin CL, Brat DJ. Appin CL, et al. Cancer J. 2014 Jan-Feb;20(1):66-72. doi: 10.1097/PPO.0000000000000020. Cancer J. 2014. PMID: 24445767 Review.
Grades II and III astrocytomas, as well as secondary GBMs are characterized by IDH1, TP53, and ATRX mutations, whereas oligodendrogliomas most frequently harbor codeletion of 1p/19q and mutations in CIC, FUBP1, and the TERT promoter. Primary GBMs frequently show molecular …
Grades II and III astrocytomas, as well as secondary GBMs are characterized by IDH1, TP53, and ATRX mutations, whereas oligodendrogliomas mo …
Mutations in CIC and FUBP1 contribute to human oligodendroglioma.
Bettegowda C, Agrawal N, Jiao Y, Sausen M, Wood LD, Hruban RH, Rodriguez FJ, Cahill DP, McLendon R, Riggins G, Velculescu VE, Oba-Shinjo SM, Marie SK, Vogelstein B, Bigner D, Yan H, Papadopoulos N, Kinzler KW. Bettegowda C, et al. Science. 2011 Sep 9;333(6048):1453-5. doi: 10.1126/science.1210557. Epub 2011 Aug 4. Science. 2011. PMID: 21817013 Free PMC article.
Among other changes, we found that the CIC gene (homolog of the Drosophila gene capicua) on chromosome 19q was somatically mutated in six cases and that the FUBP1 gene [encoding far-upstream element (FUSE) binding protein] on chromosome 1p was somatically mutated in two tu …
Among other changes, we found that the CIC gene (homolog of the Drosophila gene capicua) on chromosome 19q was somatically mutated in six ca …
Molecular background of oligodendroglioma: 1p/19q, IDH, TERT, CIC and FUBP1.
Cahill DP, Louis DN, Cairncross JG. Cahill DP, et al. CNS Oncol. 2015;4(5):287-94. doi: 10.2217/cns.15.32. Epub 2015 Nov 6. CNS Oncol. 2015. PMID: 26545048 Free PMC article. Review.
More recently, recurrent molecular genetic alterations have been identified to occur concurrently with 1p/19q-codeletion, and definitively identify these tumors, including mutations in IDH1/2, CIC, FUBP1, and the TERT promoter, as well as the absence of ATRX and TP53 alter …
More recently, recurrent molecular genetic alterations have been identified to occur concurrently with 1p/19q-codeletion, and definitively i …
Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas.
Jiao Y, Killela PJ, Reitman ZJ, Rasheed AB, Heaphy CM, de Wilde RF, Rodriguez FJ, Rosemberg S, Oba-Shinjo SM, Nagahashi Marie SK, Bettegowda C, Agrawal N, Lipp E, Pirozzi C, Lopez G, He Y, Friedman H, Friedman AH, Riggins GJ, Holdhoff M, Burger P, McLendon R, Bigner DD, Vogelstein B, Meeker AK, Kinzler KW, Papadopoulos N, Diaz LA, Yan H. Jiao Y, et al. Oncotarget. 2012 Jul;3(7):709-22. doi: 10.18632/oncotarget.588. Oncotarget. 2012. PMID: 22869205 Free PMC article.
Mutations in the critical chromatin modifier ATRX and mutations in CIC and FUBP1, which are potent regulators of cell growth, have been discovered in specific subtypes of gliomas, the most common type of primary malignant brain tumors. ...This analysis allowed us to define …
Mutations in the critical chromatin modifier ATRX and mutations in CIC and FUBP1, which are potent regulators of cell growth, have be …
Molecular Markers in Low-Grade Glioma-Toward Tumor Reclassification.
Olar A, Sulman EP. Olar A, et al. Semin Radiat Oncol. 2015 Jul;25(3):155-63. doi: 10.1016/j.semradonc.2015.02.006. Epub 2015 Feb 23. Semin Radiat Oncol. 2015. PMID: 26050585 Free PMC article. Review.
In this review, we discuss the effect of the most critical molecular alterations described in diffuse (IDH1/2, 1p/19q codeletion, ATRX, TERT, CIC, and FUBP1) and circumscribed (BRAF-KIAA1549, BRAF(V600E), and C11orf95-RELA fusion) gliomas. ...
In this review, we discuss the effect of the most critical molecular alterations described in diffuse (IDH1/2, 1p/19q codeletion, ATRX, TERT …
Genomic profiles of IDH-mutant gliomas: MYCN-amplified IDH-mutant astrocytoma had the worst prognosis.
Lee K, Kim SI, Kim EE, Shim YM, Won JK, Park CK, Choi SH, Yun H, Lee H, Park SH. Lee K, et al. Sci Rep. 2023 Apr 25;13(1):6761. doi: 10.1038/s41598-023-32153-y. Sci Rep. 2023. PMID: 37185778 Free PMC article.
Next-generation sequencing (NGS) using a brain tumor-targeted gene panel, methylation profiles, and clinicopathological features were analyzed for O_IDH_mut (n = 74) in 70 patients and for A_IDH_mut (n = 95) in 90 patients. 97.3% of O_IDH_mut and 98.9% of A_IDH_mut displayed a cl …
Next-generation sequencing (NGS) using a brain tumor-targeted gene panel, methylation profiles, and clinicopathological features were analyz …
Loss of CIC and FUBP1 expressions are potential markers of shorter time to recurrence in oligodendroglial tumors.
Chan AK, Pang JC, Chung NY, Li KK, Poon WS, Chan DT, Shi Z, Chen L, Zhou L, Ng HK. Chan AK, et al. Mod Pathol. 2014 Mar;27(3):332-42. doi: 10.1038/modpathol.2013.165. Epub 2013 Sep 13. Mod Pathol. 2014. PMID: 24030748 Free article.
However, the impact of CIC and FUBP1 mutations on their protein expressions has not been examined. ...Immunohistochemical analysis revealed loss of CIC or FUBP1 protein expression in 36% (20/55) and 16% (9/55) of oligodendroglial tumors examined. ...
However, the impact of CIC and FUBP1 mutations on their protein expressions has not been examined. ...Immunohistochemical analysis re …
Incorporating Advances in Molecular Pathology Into Brain Tumor Diagnostics.
Velázquez Vega JE, Brat DJ. Velázquez Vega JE, et al. Adv Anat Pathol. 2018 May;25(3):143-171. doi: 10.1097/PAP.0000000000000186. Adv Anat Pathol. 2018. PMID: 29521646 Review.
Whole-arm 1p/19q codeletion in conjunction with IDH mutations now define oligodendrogliomas, which are also enriched for CIC, FUBP1, PI3K, NOTCH1, and TERT-p mutations. IDH-wild-type (wt) infiltrating astrocytomas are mostly primary GBMs and are characterized by EGFR, PTEN …
Whole-arm 1p/19q codeletion in conjunction with IDH mutations now define oligodendrogliomas, which are also enriched for CIC, FUBP1, …
38 results